Thakur Publication Pharmaceutical Chemistry Book
| Author’s Name | Dr. Desh Deepak pandey |
| Book Editions | Latest Edition |
| Publishers | Thakur Publication Pvt. Ltd. |
| Price | Rs. 335 |
Nirali Prakashan Pharmaceutical Chemistry Book
| Author’s Name | Kasture, Wadokar & Kulkarni |
| Book Editions | Latest Edition |
| Publishers | Nirali Prakashan |
| Price | Rs. 310 |
Pharmaceutical Chemistry Books Topic-wise Summary
✓ Introduction to Pharmaceutical Chemistry
Pharmaceutical Chemistry deals with the preparation, assay methods, and uses of the inorganic agents used as pharmaceutical aids and as therapeutic and diagnostic agents. The acids, base, buffer and antioxidants, water, etc are the products used as pharmaceutical aids.
✓ Impurities in Pharmaceuticals
Impurity in pharmaceutical chemistry is classified as any ingredient that is not an entity defined as a drug substance. Furthermore, in a drug product, any component that is not a formulation component is considered an impurity.
✓ Volumetric Analysis
Volumetric analysis is a chemical analytical procedure based on the measurement of reaction volumes in solutions. It uses titration to determine the concentration of a solution by carefully measuring the volume of one solution needed to react with another.
✓ Gravimetric Analysis
Gravimetric analysis is a method of quantitative chemical analysis in which the component of interest is converted into a substance that can be separated from the sample and weighed the materials.
✓ Inorganic Pharmaceuticals: Pharmaceutical formulations, market preparations, storage conditions, and uses of
Haematinics: Ferrous sulfate, Ferrous fumarate, Ferric ammonium citrate, Ferrous ascorbate, Carbonyl iron
Gastrointestinal Agents: For the treatment of the gastrointestinal disease of more serious conditions the inorganic drugs used are acidifying agents which change the gastric pH and protect from intestinal harm.
Antacids: antacids are substances that reduce the problem of gastric acidity, increasing the pH of the stomach and duodenum.
Examples of Antacids are Aluminium hydroxide gel, Calcium Carbonate, Acidifying agents, Magnesium hydroxide, Magaldrate, Sodium bicarbonate, Calcium Carbonate, Adsorbents, Protectives, Calcium Carbonate, and Cathartics.
Topical agents: Topical agents are used for external use only on the body surface. Topical application of the drugs may be accomplished within the body cavities which open the outside like oral, vaginal, etc.
Some examples of topical agents are Silver Nitrate, Boric acid, Bleaching powder, Ionic Silver, Chlorhexidine Gluconate, Hydrogen peroxide, and Potassium permanganate.
Dental products: Dental caries or tooth decay is a chronic infectious disease, called dental plague, in which the cavity agents are members of the indigenous oral flora. It is a colorless sticky mixture of bacterial products, mucin, saliva, and food tuff attached to enamel covering the dentine on the crown.
Most uses of dental products are Calcium carbonate, Sodium fluoride, Denture cleaners, Denture adhesives, and Mouthwashes.
Medicinal gases: Carbon dioxide, nitrous oxide, oxygen
✓ Introduction to the nomenclature of organic chemical systems with particular reference to heterocyclic compounds containing up to Three rings.
✓ Study of the following category of medicinal compounds concerning classification, chemical name, chemical structure, uses, stability and storage conditions, different types of formulations, and their popular brand names.
✓ Drugs Acting on Central Nervous System
Anesthetics: Thiopental Sodium, Ketamine Hydrochloride, Propofol
• Sedatives and Hypnotics
Antipsychotics: Diazepam, Alprazolam, Nitrazepam, Phenobarbital
Anticonvulsants: Chlorpromazine Hydrochloride, Haloperidol, Risperidone, Sulpiride, Olanzapine, Quetiapine, Lurasidone
Anti-Depressants: Amitriptyline Hydrochloride, Imipramine Hydrochloride, Fluoxetine, Venlafaxine, Duloxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, Paroxetine.
✓ Drugs Acting on Autonomic Nervous System
Sympathomimetic Agents
• Direct Acting: Nor-Epinephrine, Epinephrine, Phenylephrine; Dopamine, Terbutaline, Salbutamol (Albuterol), Naphazoline, Tetrahydrozoline.
• Indirect Acting Agents: Hydroxy Amphetamine, Pseudoephedrine.
• Agents With Mixed Mechanism: Ephedrine, Metaraminol
Adrenergic Antagonists
• Alpha Adrenergic Blockers: Tolazoline, Phentolamine, Phenoxybenzamine, Prazosin.
• Beta-Adrenergic Blockers: Propranolol, Atenolol, Carvedilol
Cholinergic Drugs and Related Agents
• Direct Acting Agents: Acetylcholine, Carbachol, And Pilocarpine.
• Cholinesterase Inhibitors: Neostigmine, Edrophonium Chloride, Tacrine Hydrochloride, Pralidoxime Chloride, Edrophonium Chloride, Echothiopate Iodide.
Cholinergic Blocking Agents: Atropine Sulphate, Ipratropium Bromide Synthetic Cholinergic Blocking Agents: Cyclopentolate Hydrochloride, Tropicamide, Clidinium Bromide, Dicyclomine Hydrochloride
✓ Drugs Acting on Cardiovascular System
Anti-Arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Lidocaine Hydrochloride, Lorcainide Hydrochloride, Verapamil, Phenytoin Sodium, Amiodarone, and Sotalol.
Anti-Hypertensive Agents: Propranolol, Methyldopate Hydrochloride, Clonidine Hydrochloride, Captopril, Ramipril, Hydralazine Hydrochloride, Nifedipine.
Antianginal Agents: Isosorbide Dinitrate
✓ Diuretics: Acetazolamide, Frusemide*, Bumetanide, Chlorthalidone, Metolazone, Xipamide, Benzthiazide, Spironolactone
✓ Hypoglycemic Agents: Insulin and Its Preparations, Glibenclamide, Glimepiride, Pioglitazone, Metformin, Repaglinide, Gliflozins, Gliptins.
✓ Analgesic And Anti-Inflammatory Agents: Morphine Analogues, Narcotic Antagonists; Nonsteroidal Anti-Inflammatory Agents (NSAIDs)- Aspirin, Diclofenac, Ibuprofen, Celecoxib, Mefenamic Acid, Paracetamol, Piroxicam, Aceclofenac.
✓ Anti-Infective Agents: Antifungal Agents: Amphotericin-B, Griseofulvin, Miconazole, Ketoconazole, Itraconazole, Griseofulvin, Fluconazole, Naftifine Hydrochloride.
Urinary Tract Anti-Infective Agents: Norfloxacin, Ofloxacin, Ciprofloxacin, Moxifloxacin.
Anti-Tubercular Agents: INH, Ethambutol, Rifampicin, Bedaquiline, Delamanid, Para Amino Salicylic Acid, Pyrazinamide, Pretomanid.
Antiviral Agents: Amantadine Hydrochloride, Foscarnet, Zidovudine,
Ribavirin, Remdesivir, Idoxuridine, Acyclovir, Favipiravir.
Antimalarials: Quinine Sulphate, Primaquine Phosphate, Mefloquine, Cycloguanil, Chloroquine Phosphate, Pyrimethamine, Artemisinin.
Sulfonamides: Sulfanilamide, Mafenide Acetate, Sulfadiazine, Sulfamethoxazole, Sulfacetamide, Cotrimoxazole, Dapsone.
✓ Antibiotics: Penicillin G, Amoxicillin, Cloxacillin, Tetracyclines: Doxycycline, Minocycline, Streptomycin Macrolides: Erythromycin, Azithromycin
✓ Anti-Neoplastic Agents: Cyclophosphamide, Busulfan, Fluorouracil, Methotrexate, Mercaptopurine, Doxorubicin Hydrochloride, Vinblastine Sulphate, Dactinomycin, Cisplatin, Dromostanolone Propionate.