Pharmaceutics 1 Book Pdf D.Pharm 1st Year

RM Mehta Books Pdf

Authors NameRM Mehta
EditionsLatest Edition
PublishersVallabh prakashan
LanguageEnglish

V.N. Raje Pharmaceutics Book

Authors NameV.N. Raje
EditionsThird Edition
PublishersCBS Publishers & Distributor Pvt Ltd
PriceRs. 172

Nirali Publication Pharmaceutics Book

Authors NameDr. Ashok Hajare
Book EditionsLatest Edition
PublishersNirali Prakashan
PriceRs. 335

Pharmaceutics 1 Book Topic-wise Summary

✓ History of the Pharmacy Profession

• Pharmacy is a Greek word (Pharmakon means drug or medicine) which is defined as the profession which is concerned with the art and science of Identification, Preparation, Preservation & Standardization of suitable drugs from natural and synthetic sources and their formulations.

• The professionals legally permitted to prescribe medications are physicians, dentists, veterinary doctors, and senior registered nurses, pharmacists are required by law to be experts in the preparation, distribution, and handling of drugs.

• A profession that links with the health and the chemical sciences, and it is charged with a responsibility that ensures the safe and effective use of medication.

• To being A pharmacist is the right person to look at all these aspects because he is educated and trained for this job and expert on medication.

✓ Packaging Materials

• After the manufacturer of the drugs it is necessary that these should be stored properly. The stability of the drugs during their storage depends on many factors and proper packaging.

• The pharmaceutical products are available in direct contact with the containers and closures. So improper packing and poor quality of containers may lead to deterioration of the products.

✓ Pharmaceutical Aids

• Organoleptic (Colouring, flavoring, and sweetening) age

Unit Operations

• Definition, objectives/applications, principles, construction, and workings of:

✓ Size Reduction

• Size Reduction is the process of reducing drugs into smaller pieces, coarse particles, or fine powder. This process is also called comminution.

• There are several factors affecting the size reduction. These are hardness, toughness, stickiness, materials structure, etc.

✓ Size Separation

• The process of size reduction is followed by the size separation of the powdered materials.

• During the process of size reduction, uniform particle size is becoming impossible. So a special technique is used to separate particles of specified size which is known as the ‘process of size separation’.

✓ Mixing and Homogenisation

• Mixing and Homogenisation is the most widely used operation in which two or more two substances are homogeneously mixed.

• Perfect mixing is when each particle of one material lies as nearly adjacent as possible to a particle of the other material.

• The degree of mixing is not normally practicable. The desired degree of mixing depends on the purpose of the products and the objective of mixing.

✓ Filtration

• Filtration is the process where solid particles are separated from the liquid or gas by passing through a porous medium.

• When solids are present in a very small proportion that is not exceeding one percent the process of its separation from liquid is called clarification.

Drying

• Drying means the final removal of liquids from the solid material with the help of heat.

• There are so many uses of drying in the pharmaceutical industry like drying of granules, powders, etc. For drying purposes som, many pieces of equipment are used.

✓ Extraction

• Extraction process can be defined as the treatment of the plant or animal tissues with solvent, whereby the medicinally active constituent is dissolved and the maximum inert matter remains undissolved.

• The solvent used for the extraction is known as ‘Menstruum’ and the inert insoluble materials that remain after the extraction process is called ‘Marc’.

Tablets

• Tablets can be defined as it is a solid unit dosage form of medicaments with or without suitable diluents and prepared either by molding or compression.

Capsules

• Capsules are solid dosage forms in which one or more medicinal and inert ingredients are enclosed in a small shell or container (usually of gelatin).

Liquid Oral Preparations

• Solution, syrup, elixir, emulsion, suspension, and dry powder for reconstitution

Topical Preparations

• Ointments, creams, pastes, gels, liniments and lotions, suppositories, and pessaries 8 Nasal preparations, Ear preparations

Powders and Granules

• Insufflations, dusting powders, effervescent powders, and effervescent granules

Sterile Formulations

• Injectables, eye drops, and eye ointments

Immunological Products

• Sera, vaccines, toxoids, and their manufacturing methods

Quality Control and Quality Assurance

• Definition and concepts of quality control and quality assurance, current good manufacturing practice (cGMP), Introduction to the concept of calibration and validation

Novel Drug Delivery Systems

• Introduction, Classification with examples, advantages, and challenges.

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