Pharmaceutical Impurities and General Methods of Preparation
1. The standard solution of arsenic contains
(A) Arsenious acid
(B) Arsenic acid
(C) Arsine
(D) Arsenic oxide
Ans. D) Arsenic oxide
2. One of the following limit tests is based on the Comparison of colour
(A) Limit test of sulphate
(B) Limit test of chloride
(C) Limit test of iron
(D) A & C
Ans. D) A & C
3. Thioglycolic acid is used in a limit test of iron because
(A) It provides an acidic medium
(B) It reduces ferric iron to ferrous iron
(C) It gives purple coloured complex with iron
(D) B & C
Ans. D) B & C
4. Inorganic compounds generally do not Contain……… atoms
(A) Nitrogen
(B) Carbon
(C) Oxygen
(D) Sulphur
Ans. B) Carbon
5. Washing soda is
(A) Sodium carbonate
(B) Sodium bicarbonate
(C) Sodium sulphite
(D) Sodalimne
Ans. A) Sodium carbonate
6. What is added in preparation of barium Sulphate reagent to prevent super Saturation
(A) Ethanol
(B) BaCl2
(C) K2S04
(D) A & B
Ans. A) Ethanol
7. The function of granulated Zn in the limit test For Arsenic is
(A) Low and prolonged evolution of Nascent H2 gas
(B) High and prolonged evolution of Nascent H2 gas
(C) Low and prolonged evolution of Nascent N2 gas
(D) Low and prolonged evolution of Nascent N2 gas
Ans. A) Low and prolonged evolution of Nascent H2 gas
8. The reagent used in a limit test of chloride
(A) Silver nitrate
(B) Nitric acid
(C) Nitric oxide
(D) All of these
Ans. A) Silver nitrate
9. Limit test for Pb has been based b/w……. And….. upon reaction to form Complex
(A) Pb and dithionite
(B) Guizet test
(C) Arsine
(D) Mercuric chloride
Ans. A) Pb and dithionite
10. Limit test for Heavy Metals is carried out To identify and control impurities
(A) Mercury
(B) Cadmium
(C) Bismuth
(D) All of the above
Ans. D) All of the above
11. Colour produced in mercuric chloride Paper in a limit test of arsenic
(A) Yellow
(B) Red
(C) Blue
(D) Pink
Ans. A) Yellow
12. In the limit test for chloride, the standard Solution is a
(A) 0.0824% w/v sodium chloride solution
(B) 5.85 % w/v sodium chloride solution
(C) 1 % hydrochloric acid solution
(D) 1 M hydrochloric acid solution
Ans. A) 0.0824% w/v sodium chloride solution
13. Lead-dithizone complex is in colour
(A) Purple
(B) Violet
(C) Red
(D) Green
Ans. C) Red
14. Ferrous thioglycollate in acidic solution Shows
(A) Colourless
(B) Pink
(C) Purple
(D) Yellow
Ans. A) Colourless
15. The reagent used in a limit test of sulphate ion
(A) Barium sulphate reagent
(B) Barium chloride solution
(C) Barium nitrate
(D) Barium oxide
Ans. A) Barium sulphate reagent
Buffers, Electrolytes and Dental Products MCQ
1. Extracellular fluid includes
(A) Vascular fluid only
(B) Intestinal and vascular fluid
(C) Intestinal fluid only
(D) None of these
Ans. B) Intestinal and vascular fluid
2. The basic objective of replacement therapy is
(A) To restore the volume and composition of body fluids
(B) To restore the volume only
(C) To restore the composition of body fluids only
(D) None of these
Ans. A) To restore the volume and composition of body fluids
3. Buffer solutions are those which resist the Change in
(A) PH
(B) Colour
(C) Acidity
(D) Alkalinity
Ans. A) PH
4. ORS has a composition of a) NaCl, b) KCI, c) Sodium citrate, d) Sodium bicarbonate, e) Glucose
(A) A, b, c, d
(B) A, b, c, e
(C) A, b, d, e
(D) B, C, d, e
Ans. B) A, b, c, e
5. Sodium Metaphosphate is also known as
(A) Precipitated chalk
(B) Both a and b
(C) Madrell’s salt
(D) None of these
Ans. C) Madrell’s salt
6. The principal function of chloride is
(A) Maintenance of proper hydration
(B) Maintenance of Osmotic pressure
(C) Normal Electrolytic balance
(D) All of the above
Ans. D) All of the above
7. Potassium therapy is contraindicated in patient
(A) Impaired renal function
(B) Acute dehydration
(C) Myotonia congenital
(D) All of the above
Ans. D) All of the above
8. Which of the following is desensitizing agents
(A) Zinc chloride
(B) Strontium chloride
(C) Both a & b
(D) Sodium fluoride
Ans. C) Both a & b
9. What is the full form of pH
(A) Positive hydrogen
(B) Potential Hydrogen
(C) Positron
(D) Proton of hydrogen
Ans. B) Potential Hydrogen
10. Which of the following is not a property of the base
(A) Taste bitter
(B) React with salts to form acid
(C) Turn red litmus blue
(D) Feel slippery on the skin
Ans. B) React with salts to form acid
11. What is the concentration of pure water
(A) 55.51 M
(B) 25.51 M
(C) 55 M
(D) 25 M
Ans. A) 55.51 M
12. Acute metabolic alkalosis may be Corrected by
(A) KCI
(B) NaCl
(C) NaHCO3
(D) CaCl2
Ans. B) NaCl
13. Which vitamin is necessary for tooth formation
(A) Vitamin A
(B) Vitamin D
(C) Vitamin C
(D) All of the above
Ans. D) All of the above
14. The strength of a Bronsted acid depends upon its tendency to…..a proton
(A) Gain
(B) Donate
(C) React with
(D) None of these
Ans. C) React with
15. The process of removal of tartar from teeth is known as
(A) Bleaching
(B) Polishing
(C) Root canal
(D) Scaling
Ans. D) Scaling
Gastrointestinal Agents MCQ with Answers
1. Example of antacid
(A) Sodium Bicarbonate
(B) Calcium Hydroxide
(C) Magnesium Sulphate
(D) All of these
Ans. D) All of these
2. Burnett syndrome is associated with the prolonged use of
(A) Calcium-containing antacids
(B) Magnesium-containing antacid
(C) Aluminium containing antacid
(D) All of the above
Ans. A) All of the above
3. A combination of antacids is prepared because
(A) To attain the synergistic effect
(B) To enhance the antacid effect
(C) An attempt to balance the consti- passive effect of calcium and aluminium with the laxative effect of magnesium
(D) All of these
Ans. C) An attempt to balance the consti- passive effect of calcium and aluminium with the laxative effect of magnesium
4. Bismuth Sub carbonate is used as
(A) Antidiarrheal
(B) Mild antacid
(C) Mild antiseptic and astringent
(D) All of these
Ans. D) All of these
5. The drug which promotes defecation is Called
(A) Purgative
(B) Laxative
(C) Cathartic
(D) Protective
Ans. A) Purgative
6. Expectorants are used in the treatment of the Respiratory tract by
(A) Increase viscosity of bronchial sec
(B) decrease Viscosity of bronchial sec
(C) Increase Amount of refractory tract fluid a demulcent action is an extract
(D) Both (b) and (c)
Ans. A) Increase viscosity of bronchial sec
7. The condition in which excessive secretion Of gastric HCL is called as
(A) Achlorhydria
(B) Hyperchlorhydria
(C) Hypoacidity
(D) None of the above
Ans. B) Hyperchlorhydria
8. Aluminium hydroxide gel is used as
(A) Cathartic
(B) Protective and absorbent
(C) Acidifying agent
(D) Antacids
Ans. D) Antacids
9. A combination of antacids is Used because
(A) Reduces constipation effect
(B) Reduce laxative action
(C) Produces synergistic action
(D) All the above
Ans. D) All the above
10. Which is not a class of topical agents
(A) Antibiotic
(B) Protectives
(C) Antimicrobial
(D) Astringents
Ans. A) Antibiotic
11. Replacement therapy is needed
(A) Heavy loss of water
(B) Prolonged fever
(C) Diarrhoea
(D) All of the above
Ans. D) All of the above
12. The inorganic agent used to treat the GIT agent
(A) Products for altering the gastric PH
(B) Productive for intestinal inflammation
(C) Adsorbents for intestinal toxins
(D) All of the above
Ans. D) All of the above
13. Antiflatulents are generally included in Antacid formulation. They act by
(A) Reducing the surface tension of bubbles in the stomach
(B) Avoid absorption of antacid
(C) Prevent the formation of HCL
(D) All of the above
Ans. A) Reducing the surface tension of bubbles in the stomach
14. Lubricant cathartics act by
(A) Increasing bulk of intestinal content
(B) Creasing osmotic pressure in the GI tract
(C) Smooth clearance & lubricating faecal matter
(D) None of the above
Ans. C) Smooth clearance & lubricating faecal matter
15. Calcium containing nine antacids differs from Aluminium containing antacids
(A) Depend upon their basic property
(B) Do not have any amphoteric effect
(C) Do not cause systemic alkalosis
(D) All of the above
Ans. D) All of the above
Expectorants, Emetics, Haematinics & Poison MCQ
1. Alum is commonly used as
(A) Anti-infective
(B) Astringent
(C) Protectives
(D) All of these
Ans. B) Astringent
2. The progastrokinetic action of the Following drug(S) is attenuated by atropine
(A) Domperidone
(B) Metoclopramide
(C) Cisapride
(D) Both ‘b’ and ‘c’
Ans. D) Both ‘b’ and ‘c’
3. Ondansetron blocks emetogenic impulses At the following site(s)
(A) Vagal afferents in intestines
(B) Nucleus tractus solitarius
(C) Chemoreceptor trigger zone
(D) All of the above
Ans. D) All of the above
4. All of the following symptoms can occur With Ciguatera poisoning
(A) Myalgias
(B) Flushing
(C) Metallic taste
(D) Reversal of temperature sensation
Ans. B) Flushing
5. Indicate the drug which does not improve Lower oesophagal sphincter tone or Prevent gastroesophageal reflux, but is used as first-line treatment of Gastro oesophagal reflux disease
(A) Sodium alginate + Aluminium hydroxide gel
(B) Omeprazole
(C) Mosapride
(D) Famotidine
Ans. A) Sodium alginate + Aluminium hydroxide gel
6. Ferrous sulfate is also known as
(A) Blue vitriol
(B) Caustic potash
(C) Condy’s Crystals
(D) Melanterite
Ans. D) Melanterite
7. How do astringents act
(A) Lipid precipitant
(B) Protein precipitant
(C) Bacterial inhibition
(D) Both b and c
Ans. D) Both b and c
8. After inhalation oxygen combines with haemoglobin the formed complex is
(A) Carboxyhaemoglobin
(B) Oxyhaemoglobin
(C) Dioxyhemoglobin
(D) Carboxyhaemoglobin
Ans. B) Oxyhaemoglobin
9. The requirements for Folic acid in pregnant Women is
(A) 0.8 mg/day
(B) 1 mg/day
(C) 0.1 mg/day
(D) 0.3 mg/day
Ans. A) 0.8 mg/day
10. Zinc sulphate is prepared by the action of ………On Zinc Oxide
(A) Conc. HCI
(B) Conc. H2S04
(C) Conc. HN03
(D) None of these
Ans. B) Conc. H2S04
11. Which of the following antidotes is not used in cyanide poisoning
(A) Hydroxy cobalamine
(B) Sodium nitrite
(C) Sodium calcium EDTA
(D) Both a and b
Ans. D) Both a and b
12. Sodium nitrite is a …….. antidote
(A) Physiological
(B) Mechanical
(C) Chemical
(D) All of the above
Ans. A) Physiological
13. Which prokinetic drug(s) produce(s) extrapyramidal side effects
(A) Metoclopramide
(B) Cisapride
(C) Domperidone
(D) All of the above
Ans. A) Metoclopramide
14. Antidote used in paracetamol poisoning
(A) Acetylcysteine
(B) Desferioxime
(C) Vitamin K
(D) All
Ans. A) Acetylcysteine
15. Metoclopramide has the following actions Except
(A) Increases lower oesophageal sphincter tone
(B) Increases tone of the pyloric sphincter
(C) Increases gastric peristalsis
(D) Increases intestinal peristalsis
Ans. B) Increases tone of the pyloric sphincter
Radiopharmaceuticals MCQ with Answers
1. The age of a tree is determined using radio-Isotope of
(A) Phosphorus
(B) Iodine
(C) Cobalt
(D) Carbon
Ans. D) Carbon
2. Which of the following acts as quenching Gas in Geiger Muller counter
(A) Alcohol
(B) Argon gas
(C) Krypton
(D) Hydrogen
Ans. A) Alcohol
3. What problem might you foresee in Labelling a drug as shown
(A) The isotope could be easily lost since it is exchangeable with water
(B) The isotope could be lost as a result of a metabolic oxidation
(C) The isotope could be lost since it is acidic
(D) The isotope could be lost as a result of hydrolysis
Ans. D) The isotope could be lost as a result of hydrolysis
4. The S.I. unit of radioactivity is
(A) Roentgen
(B) Becquerel
(C) Curie
(D) Rutherford
Ans. B) Becquerel
5. The half-life period of radium is 1600 Years. Its average lifetime will be
(A) 4800 years
(B) 2319 years
(C) 3200 years
(D) 4217 years
Ans. B) 2319 years
6. The effect of radioactive particles passing Through biological tissue depends upon
(A) The ability of the radiation to penetrate tissue
(B) The energy of radiation
(C) The dose rate of the radiation
(D) All of the above
Ans. D) All of the above
7. Radioactivity is due to
(A) Stable electronic configuration
(B) Stable nucleus
(C) Unstable electronic configuration
(D) Unstable nucleus
Ans. D) Unstable nucleus
8. When the difference between the mass Number and atomic number of atoms of Two or more elements are the same, the atoms Are known as
(A) Isotopes
(B) Isotones
(C) Isobars
(D) Nuclear isomers
Ans. B) Isotones
9. 1 Becquerel is equivalent to
(A) 2.7 x 10-11 curie
(B) 2.7 x 10-10 curie
(C) 2.7 x 10-8 curie
(D) 2.7 x 10-5 curie
Ans. A) 2.7 x 10-11 curie
10. A device used for the measurement of Radioactivity is a
(A) Mass spectrophotometer
(B) Nuclear reactor
(C) Cyclotron
(D) G.M. Counter
Ans. D) G.M. Counter
11. The given below is used for the diagnosis of Malignant neoplasm
(A) Phosphorus-32
(B) Chromium -51
(C) Cobalt-57
(D) lodine-131
Ans. A) Phosphorus-32
12. Gamma rays are electromagnetic Radiations with a wavelength
(A) Much larger than those of light
(B) Much shorter than those of light
(C) Equal to light
(D) None of the above
Ans. B) Much shorter than those of light
13. Gaseous compounds containing Radioactive sources can be directly Introduced into the ionization chamber But which compound can not be directly Introduced into the ionization chamber
(A) Liquid samples cannot be introduced directly
(B) Solid samples cannot be introduced directly
(C) Foam samples cannot be introduced directly
(D) None of these
Ans. A) Liquid samples cannot be introduced directly
14. Which of the given are the biological effects Of Radiation
(A) Somatic effects
(B) Genetic effects
(C) Skin damage
(D) All of the above
Ans. D) All of the above
15. The particle that possesses half integral Spin as
(A) Proton
(B) Photon
(C) K-meson
(D) Pion
Ans. A) Proton