Pharmaceutical Analysis Notes Pdf Free Available For Download. Pharmaceutical Analysis 1st Semester Notes Pdf includes the most important topics such as Dosage forms, Powders, Liquid Dosage Forms, Emulsion, Suspension and Suppositories etc.
Definition, Types of Error, Determinate Error, Indeterminate Error, Operational and Personal Error, Instrumental and Reagent Errors, Errors of Method, Additive or Proportional Errors, Salient Features of Indeterminate Errors.
Calibration of Instruments, Apparatus and Applying Necessary Corrections, Performing a Parallel Control Determination, Blank Determination, Cross-checking Results by Different Methods of Analysis, Method of Standard Addition, Method of Internal Standards.
The raw material used in manufacture, Reagents used in the manufacturing process, Method/ process in manufacture or method of manufacturing, and Chemical processes used in the manufacture.
Atmospheric contamination during the manufacturing process, Intermediate products in the manufacturing process, Defects in the manufacturing process, Manufacturing hazards, and Inadequate Storage conditions.
Decomposition of the product during storage, Accidental substitution or deliberate adulteration with spurious or useless materials.
Introduction, Limit test for chlorides, Limit test for sulphates, Limit test for Iron, Limit test for Heavy metals, Limit test for Lead, Limit test for Arsenic, Modified Limit test for chlorides, Modified Limit test for sulphates.
Precipitation titration Definition, Titration curves for precipitation titrations, Endpoint detection precipitation titration, Complex formation titration, Titration curve for complexation titration, Composition of EDTA solution as a function of pH, Indicators for EDTA titration, Solubility.
Introduction, Bonding in Complexes, Werner’s Co-ordination Number, Classification of Ligands, Chelating agent, Reagent EDTA, Effect of pH on complex formation, Principle of Complexometric Titration, Methods of End Point Detection, Masking and Demasking Agents.
Definition, Criteria, Procedures, Advantages and Disadvantages, Calculations, How do we get a percentage, Gravimetric Error, Mechanism of Precipitation.
Condition for diazotization, Rate of titration, Temperature, Visual endpoint determination method, Electrometric End Point determination method, Application of diazotization titration.
Introduction, Strong Acid with a Strong Base, e.g. HCl with NaOH, Weak Acid with a Strong Base, e.g. acetic acid with NaOH, Strong Acid with a Weak Base, e.g. sulphuric acid with dilute ammonia, Weak Acid with a Weak Base, Mixture of a Strong Acid and a Weak Acid vs. a Strong Base or a Weak Base.
General Principle, The Glass Electrode for pH Measurements, Potentiometric Titrations, End-Point Detection with Potentiometric Titrations, Reagent and Apparatus, Procedures.
Introduction, Polarization, Modes of Transport of Electroactive species to DME, Polarogram, Polarographic Maxima, ILkovic Equations, Advantages and Disadvantages of DME, Application of Polarography.
Q1. What is the Pharmaceutical Analysis and their types?
Ans. Pharmaceutical analysis is a branch of chemistry which involves a series of processes for the identification, determination, and purification of a substance, Separation of the components of a solution or determination of the structure of the chemical compounds.
Q2. How many types of Pharmaceutical Analysis are there?
Ans. Generally, three are there for the analysis of the pharmaceutical sample. The manual method of analysis: Taste, smell, colour, and appearance are some of the organoleptic qualities that the senses can perceive.
Q3. What are the different techniques of Pharmaceutical Analysis?
Ans. There are three basic types of pharmaceutical analytical techniques are: • Regression Analysis. • Grouping Methods. • Multiple Equation Models.
Q4. What is the purpose of Pharmaceutical Analysis?
Ans. Pharmaceutical analysis mainly focuses on methods to identify and quantify the potential of new drug candidates, determine their purity, and identify products and degradation of the products.
Q5. What is the Definition of Pharmaceutical Analysis?
Ans. Definition of the Pharmaceutical Analysis is the different techniques of analysis. This also deals with drugs and bulk drug substances as well as pharmaceutical products.
Thanks for sharing the questions.